4.0 Era is closely related to modernization, where all materialist needs are easily met. On the other hand, it also comes with various problems. Spirituality (Sufism) is the teaching of Islam that can provide the best solution to these problems. This study aims to explore the psychological crisis arising from modernization. This research used was a qualitative method by collecting primary data and library research. This study reveals that the problems arising in the 4.0 era is a spiritual emptiness that results in psychological crisis and spirituality plays an important role to provide peace of mind in this era.