During the teaching practice program, EFL student-teachers faced various challenges in teaching English. Therefore, they need strategies to cope with them. This study intended to examine the challenges in teaching English as well as the strategies used by EFL student-teachers by using the qualitative research method. The sample of this research is five participants of EFL student-teachers who got teaching practice programs in Dayah Modern Yapena Arun. Semi-structured interviews were used to collect data by implementing qualitative concepts in data analysis with an interactive model. The result of the investigation revealed five challenges faced by EFL student-teachers in teaching English. There was a lack of confidence, a limited understanding of learning materials, a limited mastery of teaching methods, difficulties in designing lesson plans, and difficulties in class management. Their strategies to cope with these challenges were adaptation, preparation, using different teaching methods and techniques, seeking guidance from a mentor teacher, being flexible and facilitative, and using practical examples by providing simple explanations.